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In conclusion, rabies vaccine did not provide protection against mild self-reported illness among a young and healthy group of adults attending veterinary school.Ĭlinical trial registration. In a secondary analysis, there was little evidence that sex modified the effect of vaccination on any of the evaluated outcomes, although the power to detect this was low.
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546 participants were randomized (274 to rabies vaccine and 272 to placebo). Chapters: 4, Words: 3,225, Reviews: 3, Rated: T, Complete. Author: ryl00 Allo Allo English, Rated: T Humor/General Characters: Michelle D. Ambulatory Care Sensitive conditions are conditions where timely and effective ambulatory, or out-patient, care can decrease hospitalizations by preventing the onset of an illness or condition, controlling an acute episode of an illness or managing a chronic disease or condition. (Gruber x Helga, short little missing scene from the final episode, A Winkle In Time.) All Good Things. As a secondary objective, we tested for modification of the effect of rabies vaccine on study outcomes by sex. This is the total number of hospitalizations that were potentially avoidable among people less than 65 years old. Kitts assessed the effect of a primary course of rabies vaccine on the incidence rate of weekly self-reported new episodes of common infectious disease (CID) syndromes, defined as a new episode of any one of the following syndromes in a particular week: upper respiratory illness (URI), influenza-like illness (ILI), diarrheal illness (DIA) or undifferentiated febrile illness (UFI). This phase IV, single-site, participant-blinded, randomized, placebo-controlled trial in a population of veterinary students on the rabies-free island of St. Data from randomized controlled trials are needed to assess this effect against other illnesses. Rabies vaccine–a non-live vaccine–has been associated with protection against unrelated central nervous system infections. It has been proposed that these non-specific effects differ by type of vaccine and by sex, with non-live vaccines enhancing susceptibility of females to unrelated infections, and live vaccines enhancing resistance in both sexes. Vaccines may affect recipients’ immune systems in ways that change morbidity or mortality rates to unrelated infections in vaccinated populations.